Age- and deprivation-related inequalities in identification of people at high risk of type 2 diabetes in England

Abstract Background Early detection of intermediate hyperglycaemia, otherwise known as non-diabetic hyperglycaemia (NDH) is crucial to identify people at high risk of developing type 2 diabetes mellitus (T2DM) who could benefit from preventative interventions. Failure to identify NDH may also increa...

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Main Authors: Ruth Watkinson (Author), Emma McManus (Author), Rachel Meacock (Author), Matt Sutton (Author)
Format: Book
Published: BMC, 2024-08-01T00:00:00Z.
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001 doaj_9d968d103f0c45d7b7d78f71b8e2314c
042 |a dc 
100 1 0 |a Ruth Watkinson  |e author 
700 1 0 |a Emma McManus  |e author 
700 1 0 |a Rachel Meacock  |e author 
700 1 0 |a Matt Sutton  |e author 
245 0 0 |a Age- and deprivation-related inequalities in identification of people at high risk of type 2 diabetes in England 
260 |b BMC,   |c 2024-08-01T00:00:00Z. 
500 |a 10.1186/s12889-024-19571-x 
500 |a 1471-2458 
520 |a Abstract Background Early detection of intermediate hyperglycaemia, otherwise known as non-diabetic hyperglycaemia (NDH) is crucial to identify people at high risk of developing type 2 diabetes mellitus (T2DM) who could benefit from preventative interventions. Failure to identify NDH may also increase the risks of T2DM-related complications at the time of T2DM diagnosis. We investigate sociodemographic inequalities in identification of NDH in England. Methods We used nationwide data from the English National Health Service (NHS) National Diabetes Audit, which includes all people who were newly identified with NDH (N = 469,910) or diagnosed with T2DM (N = 222,795) between 1st April 2019 and 31st March 2020. We used regression models to explore inequalities in the under identification of NDH by area-level deprivation and age group. Results Of those with a new T2DM diagnosis, 67.3% had no previous record of NDH. The odds of no previous NDH being recorded were higher amongst people living in more deprived areas (Odds ratio (OR) 1.15 (95% confidence intervals (CI) [1.12, 1.19]) most deprived (Q1) compared to least deprived (Q5) quintile) and younger individuals (OR 4.02 (95% CI [3.79, 4.27] under 35s compared to age 75-84)). Deprivation-related inequalities persisted after stratification by age group, with the largest inequalities amongst middle and older age groups. People living in more deprived areas and younger people also had shorter recorded NDH duration before progression to T2DM, and higher T2DM severity at the time of diagnosis. Conclusions There is under identification of NDH relative to diagnosis of T2DM amongst people living in more deprived areas and particularly amongst younger people, resulting in missed opportunities for targeted T2DM prevention efforts and potentially contributing to inequalities in T2DM prevalence and severity. More active NDH case-finding amongst these groups may be an important first step in helping to reduce inequalities in T2DM. 
546 |a EN 
690 |a Type 2 Diabetes 
690 |a Prediabetes 
690 |a Non-diabetic hyperglycaemia 
690 |a Inequalities 
690 |a Intermediate hyperglycaemia 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024) 
787 0 |n https://doi.org/10.1186/s12889-024-19571-x 
787 0 |n https://doaj.org/toc/1471-2458 
856 4 1 |u https://doaj.org/article/9d968d103f0c45d7b7d78f71b8e2314c  |z Connect to this object online.