Recent advances in culture-based gut microbiome research

Gut microbes affect the physiology of their hosts. Studying their diversity and functions is thus of utmost importance as it will open new avenues towards the discovery of new biomolecules and the treatment of diseases. Gut microbiome research is currently boosted by the unification of metagenomics,...

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Główni autorzy: Thomas C.A. Hitch (Autor), Afrizal Afrizal (Autor), Thomas Riedel (Autor), Antonios Kioukis (Autor), Dirk Haller (Autor), Ilias Lagkouvardos (Autor), Jörg Overmann (Autor), Thomas Clavel (Autor)
Format: Książka
Wydane: Elsevier, 2021-04-01T00:00:00Z.
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700 1 0 |a Afrizal Afrizal  |e author 
700 1 0 |a Thomas Riedel  |e author 
700 1 0 |a Antonios Kioukis  |e author 
700 1 0 |a Dirk Haller  |e author 
700 1 0 |a Ilias Lagkouvardos  |e author 
700 1 0 |a Jörg Overmann  |e author 
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260 |b Elsevier,   |c 2021-04-01T00:00:00Z. 
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500 |a 10.1016/j.ijmm.2021.151485 
520 |a Gut microbes affect the physiology of their hosts. Studying their diversity and functions is thus of utmost importance as it will open new avenues towards the discovery of new biomolecules and the treatment of diseases. Gut microbiome research is currently boosted by the unification of metagenomics, which has dominated the field in the last two decades, and cultivation, which is experiencing a renaissance. Each of these approaches has advantages and drawbacks that can be overcome if used synergistically. In this brief article, we summarize recent literature and own studies on the cultivation of gut microbes, provide a succinct status quo of cultured fractions and collections of isolates, and give short opinions on challenges and next steps to take. 
546 |a EN 
690 |a Gut microbiome 
690 |a Mouse 
690 |a Cultivation 
690 |a Cultured fraction 
690 |a Metagenome-assembled genomes 
690 |a Microbiology 
690 |a QR1-502 
690 |a Other systems of medicine 
690 |a RZ201-999 
655 7 |a article  |2 local 
786 0 |n International Journal of Medical Microbiology, Vol 311, Iss 3, Pp 151485- (2021) 
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