Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed

• 主要な著者: Margaret A. Taub (著者), Matthew P. Conomos (著者), Rebecca Keener (著者), Kruthika R. Iyer (著者), Joshua S. Weinstock (著者), Lisa R. Yanek (著者), John Lane (著者), Tyne W. Miller-Fleming (著者), Jennifer A. Brody (著者), Laura M. Raffield (著者), Caitlin P. McHugh (著者), Deepti Jain (著者), Stephanie M. Gogarten (著者), Cecelia A. Laurie (著者), Ali Keramati (著者), Marios Arvanitis (著者), Albert V. Smith (著者), Benjamin Heavner (著者), Lucas Barwick (著者), Lewis C. Becker (著者), Joshua C. Bis (著者), John Blangero (著者), Eugene R. Bleecker (著者), Esteban G. Burchard (著者), Juan C. Celedón (著者), Yen Pei C. Chang (著者), Brian Custer (著者), Dawood Darbar (著者), Lisa de las Fuentes (著者), Dawn L. DeMeo (著者), Barry I. Freedman (著者), Melanie E. Garrett (著者), Mark T. Gladwin (著者), Susan R. Heckbert (著者), Bertha A. Hidalgo (著者), Marguerite R. Irvin (著者), Talat Islam (著者), W. Craig Johnson (著者), Stefan Kaab (著者), Lenore Launer (著者), Jiwon Lee (著者), Simin Liu (著者), Arden Moscati (著者), Kari E. North (著者), Patricia A. Peyser (著者), Nicholas Rafaels (著者), Christine Seidman (著者), Daniel E. Weeks (著者), Fayun Wen (著者), Marsha M. Wheeler (著者), L. Keoki Williams (著者), Ivana V. Yang (著者), Wei Zhao (著者), Stella Aslibekyan (著者), Paul L. Auer (著者), Donald W. Bowden (著者), Brian E. Cade (著者), Zhanghua Chen (著者), Michael H. Cho (著者), L. Adrienne Cupples (著者), Joanne E. Curran (著者), Michelle Daya (著者), Ranjan Deka (著者), Celeste Eng (著者), Tasha E. Fingerlin (著者), Xiuqing Guo (著者), Lifang Hou (著者), Shih-Jen Hwang (著者), Jill M. Johnsen (著者), Eimear E. Kenny (著者), Albert M. Levin (著者), Chunyu Liu (著者), Ryan L. Minster (著者), Take Naseri (著者), Mehdi Nouraie (著者), Muagututi'a Sefuiva Reupena (著者), Ester C. Sabino (著者), Jennifer A. Smith (著者), Nicholas L. Smith (著者), Jessica Lasky-Su (著者), James G. Taylor, VI (著者), Marilyn J. Telen (著者), Hemant K. Tiwari (著者), Russell P. Tracy (著者), Marquitta J. White (著者), Yingze Zhang (著者), Kerri L. Wiggins (著者), Scott T. Weiss (著者), Ramachandran S. Vasan (著者), Kent D. Taylor (著者), Moritz F. Sinner (著者), Edwin K. Silverman (著者), M. Benjamin Shoemaker (著者), Wayne H.-H. Sheu (著者), Frank Sciurba (著者), David A. Schwartz (著者), Jerome I. Rotter (著者), Daniel Roden (著者), Susan Redline (著者), Benjamin A. Raby (著者), Bruce M. Psaty (著者), Juan M. Peralta (著者), Nicholette D. Palmer (著者), Sergei Nekhai (著者), Courtney G. Montgomery (著者), Braxton D. Mitchell (著者), Deborah A. Meyers (著者), Stephen T. McGarvey (著者), Angel C.Y. Mak (著者), Ruth J.F. Loos (著者), Rajesh Kumar (著者), Charles Kooperberg (著者), Barbara A. Konkle (著者), Shannon Kelly (著者), Sharon L.R. Kardia (著者), Robert Kaplan (著者), Jiang He (著者), Hongsheng Gui (著者), Frank D. Gilliland (著者), Bruce D. Gelb (著者), Myriam Fornage (著者), Patrick T. Ellinor (著者), Mariza de Andrade (著者), Adolfo Correa (著者), Yii-Der Ida Chen (著者), Eric Boerwinkle (著者), Kathleen C. Barnes (著者), Allison E. Ashley-Koch (著者), Donna K. Arnett (著者), Christine Albert (著者), Cathy C. Laurie (著者), Goncalo Abecasis (著者), Deborah A. Nickerson (著者), James G. Wilson (著者), Stephen S. Rich (著者), Daniel Levy (著者), Ingo Ruczinski (著者), Abraham Aviv (著者), Thomas W. Blackwell (著者), Timothy Thornton (著者), Jeff O'Connell (著者), Nancy J. Cox (著者), James A. Perry (著者), Mary Armanios (著者), Alexis Battle (著者), Nathan Pankratz (著者), Alexander P. Reiner (著者), Rasika A. Mathias (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Summary: Genetic studies on telomere length are important for understanding age-related diseases. Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here, we report the first sequencing-based association study for TL across ancestrally diverse individuals (European, Af...