Imipramine and Venlafaxine Differentially Affect Primary Glial Cultures of Prenatally Stressed Rats

• Main Authors: Ewa Obuchowicz (Author), Anna Bielecka-Wajdman (Author), Michał Zieliński (Author), Grzegorz Machnik (Author), Miłosz Gołyszny (Author), Tomasz Ludyga (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, we examine the effects of prenatal administration of two antidepressants-imipramine (IMI) and venlafaxine (VEN)-on morphology and activity of a primary glial culture. Microglia are targeted by antidepressants used for antenatal depression and are important regulators of central nervous system...