Roles of host proteases in the entry of SARS-CoV-2

• Main Authors: Alexandria Zabiegala (Author), Yunjeong Kim (Author), Kyeong-Ok Chang (Author)
• 格式: 图书
• 出版: BMC, 2023-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract The spike protein (S) of SARS-CoV-2 is responsible for viral attachment and entry, thus a major factor for host susceptibility, tissue tropism, virulence and pathogenicity. The S is divided with S1 and S2 region, and the S1 contains the receptor-binding domain (RBD), while the S2 contains t...