N-Succinylaspartic-Acid-Conjugated Riluzole Is a Safe and Potent Colon-Targeted Prodrug of Riluzole against DNBS-Induced Rat Colitis

In our previous study, riluzole azo-linked to salicylic acid (RAS) was prepared as a colon-targeted prodrug of riluzole (RLZ) to facilitate the repositioning of RLZ as an anticolitic drug. RAS is more effective against rat colitis than RLZ and sulfasalazine, currently used as an anti-inflammatory bo...

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Main Authors: Jaejeong Kim (Author), Changyu Kang (Author), Jin-Wook Yoo (Author), In-Soo Yoon (Author), Yunjin Jung (Author)
Format: Book
Published: MDPI AG, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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