N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression

• Autores principales: Xun Xi (Autor), Zi-Xuan Li (Autor), Yi Zhao (Autor), Hong Liu (Autor), Shuai Chen (Autor), Dong-Xu Liu (Autor)
• Formato: Libro
• Publicado: Elsevier, 2022-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background/purpose: Mechanical stress plays a vital role in osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Cyclic mechanical stress may up-regulate reactive oxygen species (ROS) level. N-acetylcysteine (NAC) possesses powerful antioxidant capacity. However, it is undefined t...