Combined Immune Therapy for the Treatment of Visceral Leishmaniasis.

• Main Authors: Rebecca J Faleiro (Author), Rajiv Kumar (Author), Patrick T Bunn (Author), Neetu Singh (Author), Shashi Bhushan Chauhan (Author), Meru Sheel (Author), Fiona H Amante (Author), Marcela Montes de Oca (Author), Chelsea L Edwards (Author), Susanna S Ng (Author), Shannon E Best (Author), Ashraful Haque (Author), Lynette Beattie (Author), Louise M Hafner (Author), David Sacks (Author), Susanne Nylen (Author), Shyam Sundar (Author), Christian R Engwerda (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic disease caused by infections, cancer or autoimmunity can result in profound immune suppression. Immunoregulatory networks are established to prevent tissue damage caused by inflammation. Although these immune checkpoints preserve tissue function, they allow pathogens and tumors to persist, a...