Acinetobacter baumannii Infection and IL-17 Mediated Immunity
Acinetobacter baumannii is a significant cause of severe hospital-acquired infections with a recent rise in multidrug-resistant infections involving traumatic wounds of military personnel. The interleukin-17 (IL-17) pathway is essential for neutrophil recruitment in response to a variety of pathogen...
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| Main Authors: | , , , , |
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| Format: | Book |
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Hindawi Limited,
2016-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Acinetobacter baumannii is a significant cause of severe hospital-acquired infections with a recent rise in multidrug-resistant infections involving traumatic wounds of military personnel. The interleukin-17 (IL-17) pathway is essential for neutrophil recruitment in response to a variety of pathogens, while the control of A. baumannii infection is known to be dependent on neutrophils. This suggests that IL-17 may play an important role in A. baumannii infection; however, this has yet to be studied. Here, we summarize the recent advances in understanding the host-pathogen interaction of A. baumannii and propose a potential role of the IL-17 pathway in generating a protective immune response. |
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| Item Description: | 0962-9351 1466-1861 10.1155/2016/9834020 |