Single, community-based blood glucose readings may be a viable alternative for community surveillance of HbA1c and poor glycaemic control in people with known diabetes in resource-poor settings
Background: The term HbA1c (glycated haemoglobin) is commonly used in relation to diabetes mellitus. The measure gives an indication of the average blood sugar levels over a period of weeks or months prior to testing. For most low- and middle-income countries HbA1c measurement in community surveilla...
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Taylor & Francis Group,
2016-08-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_9f14a089bd9d4b9e9ff6dd9281f6a76d | ||
042 | |a dc | ||
100 | 1 | 0 | |a Daniel D. Reidpath |e author |
700 | 1 | 0 | |a Nowrozy K. Jahan |e author |
700 | 1 | 0 | |a Devi Mohan |e author |
700 | 1 | 0 | |a Pascale Allotey |e author |
245 | 0 | 0 | |a Single, community-based blood glucose readings may be a viable alternative for community surveillance of HbA1c and poor glycaemic control in people with known diabetes in resource-poor settings |
260 | |b Taylor & Francis Group, |c 2016-08-01T00:00:00Z. | ||
500 | |a 1654-9880 | ||
500 | |a 10.3402/gha.v9.31691 | ||
520 | |a Background: The term HbA1c (glycated haemoglobin) is commonly used in relation to diabetes mellitus. The measure gives an indication of the average blood sugar levels over a period of weeks or months prior to testing. For most low- and middle-income countries HbA1c measurement in community surveillance is prohibitively expensive. A question arises about the possibility of using a single blood glucose measure for estimating HbA1c and therefore identifying poor glycaemic control in resource-poor settings. Design: Using data from the 2011-2012 US National Health and Nutrition Examination Surveys, we examined the relationship between HbA1c and a single fasting measure of blood glucose in a non-clinical population of people with known diabetes (n=333). A linear equation for estimating HbA1c from blood glucose was developed. Appropriate blood glucose cut-off values were set for poor glycaemic control (HbA1c≥69.4 mmol/mol). Results: The HbA1c and blood glucose measures were well correlated (r=0.7). Three blood glucose cut-off values were considered for classifying poor glycaemic control: 8.0, 8.9, and 11.4 mmol/L. A blood glucose of 11.4 had a specificity of 1, but poor sensitivity (0.37); 8.9 had high specificity (0.94) and moderate sensitivity (0.7); 8.0 was associated with good specificity (0.81) and sensitivity (0.75). Conclusions: Where HbA1c measurement is too expensive for community surveillance, a single blood glucose measure may be a reasonable alternative. Generalising the specific results from these US data to low resource settings may not be appropriate, but the general approach is worthy of further investigation. | ||
546 | |a EN | ||
690 | |a diabetes | ||
690 | |a blood glucose | ||
690 | |a HbA1c | ||
690 | |a glycaemic control | ||
690 | |a community surveillance | ||
690 | |a developing countries | ||
690 | |a Public aspects of medicine | ||
690 | |a RA1-1270 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Global Health Action, Vol 9, Iss 0, Pp 1-7 (2016) | |
787 | 0 | |n http://www.globalhealthaction.net/index.php/gha/article/view/31691/pdf_328 | |
787 | 0 | |n https://doaj.org/toc/1654-9880 | |
856 | 4 | 1 | |u https://doaj.org/article/9f14a089bd9d4b9e9ff6dd9281f6a76d |z Connect to this object online. |