CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA

Aim. To study efficacy of testosterone undecanoate (TU) therapy in men with stable angina and androgen deficiency.Material and methods. The serum testosterone level was detected in 247 men (aged 51,6±1,8 y.o.) with stable effort angina. 60 patients with androgen deficiency additionally to basic angi...

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Main Authors: A. Ya. Kravchenko (Author), V. M. Provotorov (Author)
Format: Book
Published: Столичная издательская компания, 2016-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a A. Ya. Kravchenko  |e author 
700 1 0 |a V. M. Provotorov  |e author 
245 0 0 |a CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA 
260 |b Столичная издательская компания,   |c 2016-01-01T00:00:00Z. 
500 |a 1819-6446 
500 |a 2225-3653 
500 |a 10.20996/1819-6446-2009-5-1-37-41 
520 |a Aim. To study efficacy of testosterone undecanoate (TU) therapy in men with stable angina and androgen deficiency.Material and methods. The serum testosterone level was detected in 247 men (aged 51,6±1,8 y.o.) with stable effort angina. 60 patients with androgen deficiency additionally to basic angina therapy received TU (120-160 mg daily). 54 patients with androgen deficiency (control group) received only basic angina therapy. Dynamics of clinical and ECG manifestations of myocardial ischemia and quality of life (QOL) parameters was studied.Results. Androgen deficiency is revealed in 114 (46,2%) of patients. Therapy with TU during 3 months resulted in reduction of angina attacks and extent of myocardial ischemia (according to Holter ECG monitoring and stress test) as well as QOL improvement.Conclusion. Androgen deficiency is observed in 46,2% of men with stable angina. TU increases of antianginal therapy efficacy, improves QOL and is well tolerated. 
546 |a EN 
546 |a RU 
690 |a stable angina 
690 |a male sex 
690 |a androgen deficiency 
690 |a testosterone undecanoate 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
690 |a Diseases of the circulatory (Cardiovascular) system 
690 |a RC666-701 
655 7 |a article  |2 local 
786 0 |n Рациональная фармакотерапия в кардиологии, Vol 5, Iss 1, Pp 37-41 (2016) 
787 0 |n https://www.rpcardio.online/jour/article/view/594 
787 0 |n https://doaj.org/toc/1819-6446 
787 0 |n https://doaj.org/toc/2225-3653 
856 4 1 |u https://doaj.org/article/9f3e94e7b40b4470913e30d467ff3827  |z Connect to this object online.