Discovery of novel isoflavone derivatives as AChE/BuChE dual-targeted inhibitors: synthesis, biological evaluation and molecular modelling
AChE and BuChE are druggable targets for the discovery of anti-Alzheimer's disease drugs, while dual-inhibition of these two targets seems to be more effective. In this study, we synthesised a series of novel isoflavone derivatives based on our hit compound G from in silico high-throughput scre...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2017-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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