A case of invasive aspergillosis in CGD patient successfully treated with Amphotericin B and INF-γ
<p>Abstract</p> <p>Background</p> <p>Chronic granulomatous disease (CGD) is a rare disorder of phagocytes in which absence of superoxide and hydrogen peroxide production in phagocytes predisposes patients to bacterial and fungal infections. The most common fungal infect...
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| Main Authors: | , , , , , |
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| Format: | Book |
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BMC,
2005-03-01T00:00:00Z.
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| Summary: | <p>Abstract</p> <p>Background</p> <p>Chronic granulomatous disease (CGD) is a rare disorder of phagocytes in which absence of superoxide and hydrogen peroxide production in phagocytes predisposes patients to bacterial and fungal infections. The most common fungal infections in these patients are caused by <it>Aspergillus </it>species.</p> <p>Case presentation</p> <p>Here, we describe <it>Aspergillus </it>osteomyelitis of the ribs and hepatic abscess in a 5-year-old boy. The patient was successfully treated with Amphotericin B and INF-γ.</p> <p>Conclusion</p> <p>With respect to the high frequency of aspergillosis in the CGD patient, immune deficiency should be investigated in patients with invasive aspergillosis. Moreover, using antifungal drugs as prophylaxis can improve the quality of life in these patients.</p> |
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| Item Description: | 10.1186/1476-0711-4-4 1476-0711 |