Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp
Isatin (3a), isatin 3-carbohydrazone (4a), 5-spiro (isatin) 2-(N-acetyl hydrazino) 4-(N-acetyl)-2-1,3,4 oxadiazoline (5a), and 5-spiro (isatin) 2-hydrazino-2-1,3,4 oxadiazoline (6a) have been synthesized from unsubstituted oximinoacetanilide (2a). 4-Chlorooximinoacetanilide (2b), 5-chloroisatin (3...
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| Format: | Book |
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Bangladesh Pharmacological Society,
2007-06-01T00:00:00Z.
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| Summary: | Isatin (3a), isatin 3-carbohydrazone (4a), 5-spiro (isatin) 2-(N-acetyl hydrazino) 4-(N-acetyl)-2-1,3,4 oxadiazoline (5a), and 5-spiro (isatin) 2-hydrazino-2-1,3,4 oxadiazoline (6a) have been synthesized from unsubstituted oximinoacetanilide (2a). 4-Chlorooximinoacetanilide (2b), 5-chloroisatin (3b), 5-chloroisatin 3-carbohydrazone (4b) and 5-spiro (5-chloroisatin) 2-(N-acetyl hydrazino) 4-N-acetyl 2-1,3,4 oxadiazoline (5b) compounds have been synthesized from p-chloroaniline. The structures of the products have been characterized from spectral analysis and comparative cytotoxicity study of them was studied. |
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| Item Description: | 1991-007X 1991-0088 |