Case Report: Coexistence of Anti-Glomerular Basement Membrane Disease, Membranous Nephropathy, and IgA Nephropathy in a Female PatientWith Preserved Renal Function
The coexistence of anti-glomerular basement membrane (GBM) disease, idiopathic membranous nephropathy (IMN), and IgA nephropathy in one patient is a very rare case, which has not yet been reported. Whether the three diseases are correlated and the underlying mechanism remain unknown. Herein, we repo...
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Frontiers Media S.A.,
2022-06-01T00:00:00Z.
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| 001 | doaj_9fac36f370b6494c9c8f15c9c1f7610e | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Wei Qu |e author |
| 700 | 1 | 0 | |a Nan Liu |e author |
| 700 | 1 | 0 | |a Tianhua Xu |e author |
| 700 | 1 | 0 | |a Binyao Tian |e author |
| 700 | 1 | 0 | |a Meng Wang |e author |
| 700 | 1 | 0 | |a Yanqiu Li |e author |
| 700 | 1 | 0 | |a Jianfei Ma |e author |
| 700 | 1 | 0 | |a Li Yao |e author |
| 245 | 0 | 0 | |a Case Report: Coexistence of Anti-Glomerular Basement Membrane Disease, Membranous Nephropathy, and IgA Nephropathy in a Female PatientWith Preserved Renal Function |
| 260 | |b Frontiers Media S.A., |c 2022-06-01T00:00:00Z. | ||
| 500 | |a 1663-9812 | ||
| 500 | |a 10.3389/fphar.2022.876512 | ||
| 520 | |a The coexistence of anti-glomerular basement membrane (GBM) disease, idiopathic membranous nephropathy (IMN), and IgA nephropathy in one patient is a very rare case, which has not yet been reported. Whether the three diseases are correlated and the underlying mechanism remain unknown. Herein, we report a 48-year-old female patient that was admitted because of proteinuria and abnormal renal function, which was diagnosed as anti-GBM disease, idiopathic membranous nephropathy, and IgA nephropathy by renal biopsy. The patient received treatment including high-dose methylprednisolone pulse therapy, plasma exchange, and intravenous infusion of both cyclophosphamide (CTX) and rituximab. In the follow-up, the titer of the anti-GBM antibody gradually decreased, renal function was restored, and urinary protein was reduced, without significant adverse effects. | ||
| 546 | |a EN | ||
| 690 | |a anti-glomerular basement membrane disease | ||
| 690 | |a membranous nephropathy | ||
| 690 | |a IgA nephropathy | ||
| 690 | |a immunotherapy | ||
| 690 | |a case report | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Frontiers in Pharmacology, Vol 13 (2022) | |
| 787 | 0 | |n https://www.frontiersin.org/articles/10.3389/fphar.2022.876512/full | |
| 787 | 0 | |n https://doaj.org/toc/1663-9812 | |
| 856 | 4 | 1 | |u https://doaj.org/article/9fac36f370b6494c9c8f15c9c1f7610e |z Connect to this object online. |