Intramuscular Clodronate in Long-Term Treatment of Symptomatic Knee Osteoarthritis: A Randomized Controlled Study

• Main Authors: Bruno Frediani (Author), Carmela Toscano (Author), Paolo Falsetti (Author), Antonella Nicosia (Author), Serena Pierguidi (Author), Alberto Migliore (Author), Stefano Giannotti (Author), Luca Cantarini (Author), Edoardo Conticini (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background and Objective Clodronate is a nitrogen-free bisphosphonate that is widely and effectively used in the treatment of many osteo-metabolic disorders. The objective of our study was to evaluate the effectiveness of clodronate in reducing pain and bone marrow edema in knee osteoarthri...