Proteomic Phenotyping of Stimulated Müller Cells Uncovers Profound Pro-Inflammatory Signaling and Antigen-Presenting Capacity

• Autori principali: Adrian Schmalen (Autore), Lea Lorenz (Autore), Antje Grosche (Autore), Diana Pauly (Autore), Cornelia A. Deeg (Autore), Stefanie M. Hauck (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Müller cells are the main macroglial cells of the retina exerting a wealth of functions to maintain retinal homoeostasis. Upon pathological changes in the retina, they become gliotic with both protective and detrimental consequences. Accumulating data also provide evidence for a pivotal role of Müll...