Proteomic Phenotyping of Stimulated Müller Cells Uncovers Profound Pro-Inflammatory Signaling and Antigen-Presenting Capacity

• Ngā kaituhi matua: Adrian Schmalen (Author), Lea Lorenz (Author), Antje Grosche (Author), Diana Pauly (Author), Cornelia A. Deeg (Author), Stefanie M. Hauck (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Müller cells are the main macroglial cells of the retina exerting a wealth of functions to maintain retinal homoeostasis. Upon pathological changes in the retina, they become gliotic with both protective and detrimental consequences. Accumulating data also provide evidence for a pivotal role of Müll...