Inflammation as a Cancer Co-Initiator: New Mechanistic Model Predicts Low/Negligible Risk at Noninflammatory Carcinogen Doses
Linear-no-threshold (LNT) risk extrapolation has long been applied to estimate risks posed by low-level environmental carcinogen exposures, based on the 60-year-old multistage somatic mutation/clonal expansion (MSM) cancer theory. Recent evidence supports an alternative theory: Malignant tumors aris...
Saved in:
Main Author: | Kenneth T. Bogen (Author) |
---|---|
Format: | Book |
Published: |
SAGE Publishing,
2019-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Low-Dose Dose-Response for In Vitro Nrf2-ARE Activation in Human HepG2 Cells
by: Kenneth T. Bogen
Published: (2017) -
Mechanistic Models Fit to Ed Data on >40,000 Trout Exposed to Dibenzo[]Pyrene Indicate Mutations Do Not Drive Increased Tumor Risk
by: Kenneth T. Bogen
Published: (2014) -
Criminal Negligence
by: McComas, J. Francis, 1911-1978; Freas, Kelly, 1922-2005 [Illustrator] -
Fecal calprotectin Level in patients with IBD and noninflammatory disease of colon: a study in Babol, Northern, Iran
by: Majid Sharbatdaran, et al.
Published: (2018) -
Risk-Assessment Implications of Mechanistic Model's Prediction of Low-Dose Nonlinearity of Liver Tumor Risk for Mice FED Fumonisin B
by: Ralph L. Kodell, et al.
Published: (2004)