Optimized Methods for Analytical and Functional Comparison of Biosimilar mAb Drugs: A Case Study for Avastin, Mvasi, and Zirabev

• Main Authors: Büşra Gürel (Author), Eda Çapkın (Author), Ayhan Parlar (Author), Aylin Özkan (Author), Meltem Çorbacıoğlu (Author), Duygu Emine Dağlikoca (Author), Meral Yüce (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bevacizumab is a humanized therapeutic monoclonal antibody used to reduce angiogenesis, a hallmark of cancer, by binding to VEGF-A. Many pharmaceutical companies have developed biosimilars of Bevacizumab in the last decade. The official reports provided by the FDA and EMA summarize the analytical pe...