Co-Administration of Amiodarone Increases Bleeding by Affecting Rivaroxaban Pharmacokinetics in Patients with Atrial Fibrillation

• Main Authors: Huamin Ding (Author), Zi Wang (Author), Jia Wang (Author), Yao Yao (Author), Chi Zhang (Author), Houwen Lin (Author), Yong Zhou (Author), Zhichun Gu (Author), Qianzhou Lv (Author), Xiaoye Li (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to investigate the impact of the drug-drug interaction between rivaroxaban and amiodarone on the clinical outcomes in patients with non-valvular atrial fibrillation (NVAF), focusing on pharmacokinetic and pharmacodynamic (PK/PD) aspects. A prospective study enrolling 174 patients wi...