Shedding Light on the Hidden Benefit of <i>Porphyridium cruentum</i> Culture
Microalgae can represent a reliable source of natural compounds with different activities. Here, we evaluated the antioxidant and anti-inflammatory activity of sulfated exopolysaccharides (s-EPSs) and phycoerythrin (PE), two molecules naturally produced by the red marine microalga <i>Porphyrid...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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MDPI AG,
2023-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Microalgae can represent a reliable source of natural compounds with different activities. Here, we evaluated the antioxidant and anti-inflammatory activity of sulfated exopolysaccharides (s-EPSs) and phycoerythrin (PE), two molecules naturally produced by the red marine microalga <i>Porphyridium cruentum</i> (CCALA415). <i>In vitro</i> and cell-based assays were performed to assess the biological activities of these compounds. The s-EPSs, owing to the presence of sulfate groups, showed biocompatibility on immortalized eukaryotic cell lines and a high antioxidant activity on cell-based systems. PE showed powerful antioxidant activity both <i>in vitro</i> and on cell-based systems, but purification is mandatory for its safe use. Finally, both molecules showed anti-inflammatory activity comparable to that of ibuprofen and helped tissue regeneration. Thus, the isolated molecules from microalgae represent an excellent source of antioxidants to be used in different fields. |
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| Item Description: | 10.3390/antiox12020337 2076-3921 |