Chemical and biological investigations of Dillenia indica Linn.

A total of four compounds namely, lupeol (1), betulinaldehyde (2), betulinic acid (3) and stigmasterol (4) were isolated from the stem extract of Dillenia indica Linn. The structures of the isolated compounds (1-4) were established by extensive spectroscopic studies. The crude methanolic extracts an...

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Bibliographic Details
Main Author: Most. Nazma Parvin, Mohammad S. Rahman, Mohammad S. Islam and Mohammad A. Rashid (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2009-12-01T00:00:00Z.
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100 1 0 |a Most. Nazma Parvin, Mohammad S. Rahman, Mohammad S. Islam and Mohammad A. Rashid  |e author 
245 0 0 |a Chemical and biological investigations of Dillenia indica Linn. 
260 |b Bangladesh Pharmacological Society,   |c 2009-12-01T00:00:00Z. 
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520 |a A total of four compounds namely, lupeol (1), betulinaldehyde (2), betulinic acid (3) and stigmasterol (4) were isolated from the stem extract of Dillenia indica Linn. The structures of the isolated compounds (1-4) were established by extensive spectroscopic studies. The crude methanolic extracts and its n-hexane, carbon tetrachloride, dichloromethane and chloroform soluble partitionates demonstrated weak antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria and fungi. The extractives revealed significant cytotoxic activity when tested by brine shrimp lethality bioassay. In addition, the extractives exhibited significant free radical scavenging activity when compared with ascorbic acid. 
546 |a EN 
690 |a Antimicrobial activity 
690 |a Antioxidant activity 
690 |a Cytotoxicity 
690 |a Dillenia indica 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Bangladesh Journal of Pharmacology, Vol 4, Iss 2, Pp 122-125 (2009) 
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