Cell free DNA as a marker of training status in weightlifters
The purpose of this investigation was to elucidate the changes in cf-DNA as it relates to fluctuations in resistance training workloads and intensities. The relationship between cell free DNA (cf-DNA), C-reactive protein (CRP), creatine kinase (CK), testosterone (T), cortisol (C), testosterone-corti...
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| Format: | Book |
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Termedia Publishing House,
2017-10-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_a0cd0d6b3514426aaee21c70fc92b47c | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Jeremy A. Gentles |e author |
| 700 | 1 | 0 | |a William G. Hornsby |e author |
| 700 | 1 | 0 | |a Christine L. Coniglio |e author |
| 700 | 1 | 0 | |a Andrew R. Dotterweich |e author |
| 700 | 1 | 0 | |a Jon A. Miller |e author |
| 700 | 1 | 0 | |a Charles A. Stuart |e author |
| 700 | 1 | 0 | |a Michael H. Stone |e author |
| 245 | 0 | 0 | |a Cell free DNA as a marker of training status in weightlifters |
| 260 | |b Termedia Publishing House, |c 2017-10-01T00:00:00Z. | ||
| 500 | |a 0860-021X | ||
| 500 | |a 2083-1862 | ||
| 500 | |a 10.5114/biolsport.2017.67855 | ||
| 520 | |a The purpose of this investigation was to elucidate the changes in cf-DNA as it relates to fluctuations in resistance training workloads and intensities. The relationship between cell free DNA (cf-DNA), C-reactive protein (CRP), creatine kinase (CK), testosterone (T), cortisol (C), testosterone-cortisol ratio (T:C), body mass and body composition were also examined. Eight weightlifters (5 males and 3 females, age = 25 ± 3.5 yr, body mass = 88.3 ± 22.7 kg, height = 173.8 ±8.4 cm) volunteered to participate in this study. Venous blood samples, body mass and body composition were taken six times, each corresponding to the end of a training phase. CK (p = 0.018, η² = 0.409) and CK %Δ (p < 0.001, η² = 0.594) were the only biochemical variables to reach statistical significance at any point. A number of statistically significant correlations were found among variables. VLD4wk was related to CK %Δ (r = 0.86), VLD4wk %Δ was related CK %Δ (r = 0.86) and TID1wk was related to CRP (r = 0.83). cf-DNA %Δ was correlated with CRP and CRP %Δ (r = 0.83 and 0.86, respectively). CRP and CRP %Δ were correlated with BF % (r = 0.94 and 0.92, respectively). CK and CK %Δ were both related to T:C (r = 0.94 and 0.89, respectively) and T:C %Δ (r = 0.87 and 0.86, respectively). The correlation between cf-DNA and CRP suggests that cf-DNA may be a valuable indicator of inflammation in weightlifters. | ||
| 546 | |a EN | ||
| 690 | |a Cell free DNA | ||
| 690 | |a Inflammation | ||
| 690 | |a Resistance training | ||
| 690 | |a Athlete monitoring | ||
| 690 | |a Sports medicine | ||
| 690 | |a RC1200-1245 | ||
| 690 | |a Biology (General) | ||
| 690 | |a QH301-705.5 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Biology of Sport, Vol 34, Iss 3, Pp 287-294 (2017) | |
| 787 | 0 | |n https://www.termedia.pl/Cell-free-DNA-as-a-marker-of-training-status-in-weightlifters,78,29974,1,1.html | |
| 787 | 0 | |n https://doaj.org/toc/0860-021X | |
| 787 | 0 | |n https://doaj.org/toc/2083-1862 | |
| 856 | 4 | 1 | |u https://doaj.org/article/a0cd0d6b3514426aaee21c70fc92b47c |z Connect to this object online. |