Asymmetric Total Syntheses of Both Enantiomers of Plymuthipyranone B and Its Unnatural Analogues: Evaluation of <i>anti</i>-MRSA Activity and Its Chiral Discrimination

• Main Authors: Mizuki Moriyama (Author), Xiaoxi Liu (Author), Yuki Enoki (Author), Kazuaki Matsumoto (Author), Yoo Tanabe (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chiral total syntheses of both enantiomers of the <i>anti</i>-MRSA active plymuthipyranone B and all of the both enantiomers of three unnatural and synthetic analogues were performed. These two pairs of four chiral compounds are composed of the same 3-acyl-5,6-dihydro-2<i>H</i&g...