Therapeutic Potential of Polyphenols in Cardiac Fibrosis

• Main Authors: Ning Zhang (Author), Wen-Ying Wei (Author), Ling-Li Li (Author), Can Hu (Author), Qi-Zhu Tang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiac fibrosis, in response to injury and stress, is central to a broad constellation of cardiovascular diseases. Fibrosis decreases myocardial wall compliance due to extracellular matrix (ECM) accumulation, leading to impaired systolic and diastolic function and causing arrhythmogenesis. Although...