A comparative study of the anti-inflammatory effect of aqueous extract of neem leaf and dexamethasone

The anti-inflammatory effect of aqueous extract of neem leaf (400 mg/kg body weight) was compared with that of dexamethasone (0.75 mg, intraperitoneally) by administering one hour before the formalin injection and once daily for 7 days in rats. The percentage of inhibition of paw edema in case of ne...

Full description

Saved in:
Bibliographic Details
Main Authors: Abu Syed Md. Mosaddek (Author), Md. Mamun Ur Rashid (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2008-06-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_a15eba4a5c6d49ed8099f8d1346c7c20
042 |a dc 
100 1 0 |a Abu Syed Md. Mosaddek  |e author 
700 1 0 |a Md. Mamun Ur Rashid  |e author 
245 0 0 |a A comparative study of the anti-inflammatory effect of aqueous extract of neem leaf and dexamethasone 
260 |b Bangladesh Pharmacological Society,   |c 2008-06-01T00:00:00Z. 
500 |a 1991-007X 
500 |a 1991-0088 
520 |a The anti-inflammatory effect of aqueous extract of neem leaf (400 mg/kg body weight) was compared with that of dexamethasone (0.75 mg, intraperitoneally) by administering one hour before the formalin injection and once daily for 7 days in rats. The percentage of inhibition of paw edema in case of neem after 3 hours, 6 hours, on day 3, on day 7 after formalin injection were 28%, 40%, 45%, 58% respectively and that in case of dexamethasone after 3 hours, 6 hours, on day 3, on day 7 after formalin injection were 43%, 58%, 61%, 65% respectively. The reduction was statistically significant in each case (p<0.001). The present study suggests that anti-inflammatory effect of neem extract is less than that produced by dexamethasone. 
546 |a EN 
690 |a Dexamethasone 
690 |a Neem 
690 |a Paw edema 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Bangladesh Journal of Pharmacology, Vol 3, Iss 1, Pp 44-47 (2008) 
787 0 |n http://www.bdjpharmacol.com/0301/44.pdf 
787 0 |n https://doaj.org/toc/1991-007X 
787 0 |n https://doaj.org/toc/1991-0088 
856 4 1 |u https://doaj.org/article/a15eba4a5c6d49ed8099f8d1346c7c20  |z Connect to this object online.