Prediction of biological activity of spiroquinazolone derivatives as protein kinase inhibitors FGFR1 and CK2

• 主要な著者: O. K. Farat (著者), S. A. Varenychenko (著者), V. I. Markov (著者)
• フォーマット: 図書
• 出版事項: Zaporozhye State Medical University, 2020-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The purpose. The search for FGFR1 and CK2 protein kinase inhibitors were performed among spiroquinazolone derivatives using receptor-oriented virtual screening and in vitro biochemical testing using the human CK2 kinase domain. Materials and methods. The docking was performed at ATP binding sites fo...