Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study

• Main Authors: Bikalpa Neupane (Author), Hitesh Pandya (Author), Tej Pandya (Author), Rupert Austin (Author), Neil Spooner (Author), James Rudge (Author), Hussain Mulla (Author)
• Format: Book
• Published: Wiley, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population. This study set out to determine which critical illness‐related factors impact midazolam pharmacokinetics in childre...