The role of nitric oxide in small intestine differs between a single and a consecutive administration of methotrexate to rats

The role of nitric oxide (NO) on intestinal mucosal injury induced by single or consecutive administration of methotrexate was investigated in a rodent model. Rats received methotrexate intraperitoneally either as a single administration (50 mg/kg) or as a consecutive administration (12.5 mg/kg/day)...

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Bibliographic Details
Main Authors: Saki Shiga (Author), Takuji Machida (Author), Takumi Yanada (Author), Maiko Machida (Author), Masahiko Hirafuji (Author), Kenji Iizuka (Author)
Format: Book
Published: Elsevier, 2020-05-01T00:00:00Z.
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