The Usefulness of In Vitro Percutaneous Absorption Experiments Applying the Infinite Dose Technique to Predict In Vivo Plasma Levels: Comparison of Model-Predicted and Observed Plasma Concentrations of Nortriptyline in Rats
The aims of this study were to evaluate the feasibility of a nortriptyline (NT) formulation for transdermal administration and to assess the usefulness of an estimated kinetic parameter (<i>k<sub>out</sub></i>) using the in vitro infinite dose technique to predict in vivo pla...
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Format: | Book |
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MDPI AG,
2022-07-01T00:00:00Z.
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