Electrophysiological analyses of transgenic mice overexpressing KCNJ8 with S422L mutation in cardiomyocytes
Genetic analysis of KCNJ8 has pointed a mutation (S422L) as a susceptible link to J wave syndrome (JWS). In vitro expression study indicated that the ATP-sensitive K+ (KATP) channel with the S422L mutation has the gain-of-function with reduced sensitivity to ATP. However, the electrophysiological im...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2017-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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