Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei.

• Hlavní autoři: Maria Lucia Sampaio Guther (Autor), Alan R Prescott (Autor), Sabine Kuettel (Autor), Michele Tinti (Autor), Michael A J Ferguson (Autor)
• Médium: Kniha
• Vydáno: Public Library of Science (PLoS), 2021-02-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

In Trypanosoma brucei, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete enzymes, five of which possess putative perox...