Metformin Inhibits Expression and Secretion of PEDF in Adipocyte and Hepatocyte via Promoting AMPK Phosphorylation
Objective. Pigment epithelium-derived factor (PEDF) plays an important role in obesity-induced insulin resistance (IR). The study aims to investigate the effect of metformin, a widely used agent to improve IR, on PEDF production both in vivo and in vitro. Methods. SD rats were divided into normal co...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2013-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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