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Skeletal muscle-specific overexpression of miR-486 limits mammary tumor-induced skeletal muscle functional limitations

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miR-486 is a myogenic microRNA, and its reduced skeletal muscle expression is observed in muscular dystrophy. Transgenic overexpression of miR-486 using muscle creatine kinase promoter (MCK-miR-486) partially rescues muscular dystrophy phenotype. We had previously demonstrated reduced circulating an...

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Bibliographic Details
Main Authors: Ruizhong Wang (Author), Brijesh Kumar (Author), Emma H. Doud (Author), Amber L. Mosley (Author), Matthew S. Alexander (Author), Louis M. Kunkel (Author), Harikrishna Nakshatri (Author)
Format: Book
Published: Elsevier, 2022-06-01T00:00:00Z.
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