Trends on Prevalence, All-Cause Mortality, and Survival Status of Dementia Patients in Rural China Based on Pooling Analysis

• Main Authors: Kang Huo (Author), Suhang Shang (Author), Jin Wang (Author), Chen Chen (Author), Liangjun Dang (Author), Ling Gao (Author), Shan Wei (Author), Lingxia Zeng (Author), Qiumin Qu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1661-8564; 10.3389/ijph.2024.1606786
• Keywords: dementia; prevalence; mortality; survival status; cohort study; Public aspects of medicine; RA1-1270
• Source: International Journal of Public Health, Vol 69 (2024)

ObjectivesNo study has reported secular trends in dementia prevalence, all-cause mortality, and survival status in rural China.MethodsWe established two cohorts (XRRCC1 and XRRCC2) in the same region of China, 17 years apart, to compare dementia prevalence, all-cause mortality, and survival status, and performed regression analysis to identify associated factors.ResultsDementia prevalence was 3.49% in XRRCC1 and 4.25% in XRRCC2, with XRRCC2 showing a significantly higher prevalence (OR = 1.79, 95%CI: 1.2-2.65). All-cause mortality rates for dementia patients were 62.0% in XRRCC1 and 35.7% in XRRCC2. Mortality in the normal population of XRRCC2 decreased by 66% compared to XRRCC1, mainly due to improved survival rates in women with dementia. Dementia prevalence was positively associated with age >65, spouse-absent status, and stroke, and negatively associated with ≥6 years of education.ConclusionDementia prevalence in rural China increased over 17 years, while mortality decreased. Major risk factors include aging, no spouse, and stroke, with higher education offering some protection.