The use of subgingival chlorhexidine chip in the treatment of periodontal disease
Due to the infective nature of periodontal disease several local devices have been used to overcome the limited efficacy of conventional periodontal treatment. However, local concentration of these medicaments, especially over time, raises the question of expediency of their use. Local delivery syst...
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| Main Authors: | , , |
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| Format: | Book |
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Serbian Medical Society - Dental Section, Belgrade,
2006-01-01T00:00:00Z.
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| Summary: | Due to the infective nature of periodontal disease several local devices have been used to overcome the limited efficacy of conventional periodontal treatment. However, local concentration of these medicaments, especially over time, raises the question of expediency of their use. Local delivery systems allow the therapeutic agents to be targeted to the diseased site for a long time. These systems, when retained in the periodontal pocket, can release the antimicrobial agents at levels that are 10- to 100-fold higher than the levels that can be delivered by systemic antibiotics. Several different drug delivery systems have been used in controlled clinical trials: fibers, gels and chips. The most frequently used antimicrobials are antibiotics (tetracycline, minocycline), hemotherapeutics (metronidazole), and antiseptics (chlorhexidine dicluconate). In the present paper the method of chlorhexidine chip application is analyzed. We discussed the results of studies that evaluated the efficacy of a controlled-release of biodegradable chlorhexidine chip when used as an adjust to scaling and root planning (SRP) in adult periodontitis. |
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| Item Description: | 10.2298/SGS0603181L 0039-1743 |