Thioredoxin-1 Ameliorates Oxygen-Induced Retinopathy in Newborn Mice through Modulation of Proinflammatory and Angiogenic Factors

• Main Authors: Junichi Ozawa (Author), Kosuke Tanaka (Author), Yukio Arai (Author), Mitsuhiro Haga (Author), Naoyuki Miyahara (Author), Ai Miyamoto (Author), Eri Nishimura (Author), Fumihiko Namba (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxygen-induced retinopathy (OIR) is an animal model for retinopathy of prematurity, which is a leading cause of blindness in children. Thioredoxin-1 (TRX) is a small redox protein that has cytoprotective and anti-inflammatory properties in response to oxidative stress. The purpose of this study was...