Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways

• Main Authors: Yun Yuan (Author), Qiongying Hu (Author), Lu Liu (Author), Fan Xie (Author), Luyao Yang (Author), Yuchen Li (Author), Chuantao Zhang (Author), Hongqing Chen (Author), Jianyuan Tang (Author), Xiaofei Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dehydrocostus lactone (DCL) is a major sesquiterpene lactone isolated from Aucklandia lappa Decne, a traditional Chinese herbal medicine that used to treat gastrointestinal diseases. This study aimed to examine the therapeutic effects of DCL on dextran sulfate sodium (DSS)-induced colitis with a foc...