A case of unilateral neutrophilic dermatosis of the dorsal hands

Our case focuses on a 60-year-old male patient, a farmer, with a previous diagnosis of myelodysplastic syndrome, under regular surveillance at the haemato-oncology department. The patient was referred to the emergency room with an inflammatory ulcerated plaque in the dorsum of his left hand, with 2...

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Bibliographic Details
Main Authors: Ana G. Lopes (Author), Maria J. Guimarães (Author), Catarina Cerqueira (Author), Cristiana Macedo (Author), Joana Gomes (Author), Celeste Brito (Author)
Format: Book
Published: Sociedade Portuguesa de Dermatologia e Venereologia, 2023-04-01T00:00:00Z.
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Summary:Our case focuses on a 60-year-old male patient, a farmer, with a previous diagnosis of myelodysplastic syndrome, under regular surveillance at the haemato-oncology department. The patient was referred to the emergency room with an inflammatory ulcerated plaque in the dorsum of his left hand, with 2 weeks evolution. There were two moderately swollen, very painful ulcerated plaques on the dorsal aspect of the left hand, with grayish borders and irregular margins. A skin biopsy showed panniculitis and a dense neutrophilic dermal infiltrate. Attending to his underlying disease, clinical hallmarks of the lesion, and skin biopsy, the diagnosis of a neutrophilic dermatosis of the dorsal hands was made. The patient was treated with oral prednisolone 0.5 mg/kg/day and colchicine 1mg/day with complete regression after 1 month. Neutrophilic dermatosis is a heterogeneous group of skin diseases characterized by dense infiltration of neutrophils in the affected tissue. Neutrophilic dermatosis of dorsal hands is one of them and is considered a localized variant of Sweet Syndrome. The etiology is unknown, but about half of the cases are associated with hematological diseases.
Item Description:2182-2395
2182-2409