Arthritis and Osteomyelitis due to <it>Aspergillus fumigatus</it>: A 17 years old boy with chronic granulomatous disease
<p>Abstract</p> <p>Background</p> <p>Invasive <it>Aspergillus </it>infections are frequently seen in immunocompromised patients but arthritis is a rare complication of <it>Aspergillus </it>infections in the absence of immune suppressive therapy,...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Book |
| Published: |
BMC,
2003-01-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | <p>Abstract</p> <p>Background</p> <p>Invasive <it>Aspergillus </it>infections are frequently seen in immunocompromised patients but arthritis is a rare complication of <it>Aspergillus </it>infections in the absence of immune suppressive therapy, trauma or surgical intervention.</p> <p>Case presentation</p> <p>A 17 years old male patient with arthritis and patellar osteomyelitis of the left knee whose further investigations revealed chronic granulomatous disease as the underlying disease is followed. <it>Aspergillus fumigatus </it>was isolated from the synovial fluid and the tissue samples cultures. He was treated with Amphotericin B deoxicolate 0.7 mg/kg/day. Also surgical debridement was performed our patient. Amphotericin B nephrotoxicity developed and the therapy switched to itraconazole 400 mg/day. Itraconazole therapy were discontinued at the 6th month. He can perform all the activities of daily living including.</p> <p>Conclusion</p> <p>We think that, chronic granulomatous disease should be investigated in patients who have aspergillar arthritis and osteomyelitis.</p> |
|---|---|
| Item Description: | 10.1186/1476-0711-2-2 1476-0711 |