Evaluation of soluble expression of recombinant granulocyte macrophage stimulating factor (rGM-CSF) by three different E. coli strains

• প্রধান লেখক: Sina Soheili (লেখক), Ali Jahanian-Najafabadi (লেখক), Vajihe Akbari (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background and purpose: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine with a wide range of therapeutic applications although expression of GM-CSF in Escherichia coli (E. coli) usually leads to formation of insoluble aggregates mostly lack biological activity. The aim of thi...