The Natural Compound Oblongifolin C Exhibits Anticancer Activity by Inhibiting HSPA8 and Cathepsin B In Vitro

• Main Authors: Li Han (Author), Danqing Xu (Author), Zhichao Xi (Author), Man Wu (Author), Wan Najbah Nik Nabil (Author), Juan Zhang (Author), Hua Sui (Author), Wenwei Fu (Author), Hua Zhou (Author), Yuanzhi Lao (Author), Gang Xu (Author), Cheng Guo (Author), Hongxi Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PPAPs (Polycyclic polyprenylated acylphloroglucinols) are a class of compounds with diverse bioactivities, including anticancer effects. Oblongifolin C (OC) is a PPAP isolated from the plant of Garcinia yunnanensis Hu. We previously discovered that OC induces apoptosis, inhibits autophagic flux, and...