Improving the Endosomal Escape of Cell-Penetrating Peptides and Their Cargos: Strategies and Challenges
Cell penetrating peptides (CPPs) can deliver cell-impermeable therapeutic cargos into cells. In particular, CPP-cargo conjugates tend to accumulate inside cells by endocytosis. However, they often remain trapped inside endocytic organelles and fail to reach the cytosolic space of cells efficiently....
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Main Authors: | Jean-Philippe Pellois (Author), Ting-Yi Wang (Author), Ryan Baker (Author), Nandhini Muthukrishnan (Author), Alfredo Erazo-Oliveras (Author) |
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Format: | Book |
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MDPI AG,
2012-11-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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