Synthesis, Characterization, and Biological Evaluation of Meldrum's Acid Derivatives: Dual Activity and Molecular Docking Study

• Автори: Syed Nasir Abbas Bukhari (Автор), Mohamed Abdelwahab Abdelgawad (Автор), Naveed Ahmed (Автор), Muhammad Wahab Amjad (Автор), Muhammad Ajaz Hussain (Автор), Mervat A. Elsherif (Автор), Hasan Ejaz (Автор), Nasser H. Alotaibi (Автор), Ignjat Filipović (Автор), Nenad Janković (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

In the presented study, eight novel Meldrum's acid derivatives containing various vanillic groups were synthesized. Vanillidene Meldrum's acid compounds were tested against different cancer cell lines and microbes. Out of nine, three showed very good biological activity against <i>E....