Premature Ovarian Insufficiency - diagnostic and therapeutic challenges

Introduction and purpose: Premature Ovarian Insufficiency (POI) is a rare but serious disease diagnosed in about 1% of women before the age of 40. It is characterized by hypoestrogenism and an increase in the level of the follicle-stimulating hormone, which is associated with menstrual disorders, pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Izabela Hawranik (Author), Mikołaj Tomasik (Author), Paweł Warzyszak (Author), Róża Małek (Author), Maria Milczek (Author), Wojciech Żołyniak (Author), Szymon Niski (Author), Ziemowit Żaba (Author), Aleksandra Lisowska (Author), Mateusz Skrzypek (Author)
Format: Book
Published: Nicolaus Copernicus University in Toruń, 2023-03-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_a38d0b80ed0240a984f6e6e7f28b24e5
042 |a dc 
100 1 0 |a Izabela Hawranik  |e author 
700 1 0 |a Mikołaj Tomasik  |e author 
700 1 0 |a Paweł Warzyszak  |e author 
700 1 0 |a Róża Małek   |e author 
700 1 0 |a Maria Milczek  |e author 
700 1 0 |a Wojciech Żołyniak  |e author 
700 1 0 |a Szymon Niski  |e author 
700 1 0 |a Ziemowit Żaba  |e author 
700 1 0 |a Aleksandra Lisowska  |e author 
700 1 0 |a Mateusz Skrzypek  |e author 
245 0 0 |a Premature Ovarian Insufficiency - diagnostic and therapeutic challenges 
260 |b Nicolaus Copernicus University in Toruń,   |c 2023-03-01T00:00:00Z. 
500 |a 10.12775/QS.2023.09.02.008 
500 |a 2450-3118 
520 |a Introduction and purpose: Premature Ovarian Insufficiency (POI) is a rare but serious disease diagnosed in about 1% of women before the age of 40. It is characterized by hypoestrogenism and an increase in the level of the follicle-stimulating hormone, which is associated with menstrual disorders, pregnancy failures and a reduced quality of life. The main causes of POI include a genetic background and autoimmune abnormalities, as well as increasingly jatrogenic factors. Care for patients is focused on hormone replacement therapy and infertility treatment. The aim of this review is to discuss current treatment methods, the impact of early diagnosis and the prevention of premature ovarian insufficiency, which affects the ability to have one's own offspring. The article also describes new methods of infertility treatment that are under investigation. Materials and methods: This literature review is based on articles published in the PubMed database from 2015 to 2022 using the following phrases: premature ovarian insufficiency, premature ovarian insufficiency stem cells State of knowledge: The only way to treat infertility in women with POI is egg donation. Currently, research is being conducted to achieve early diagnosis, introduce new treatment methods and reduce the number of iatrogenic forms of POI. Conclusion: The main problem for women diagnosed with POI is the difficulty or often impossibility of having their own children. Egg donation does not allow for the transfer of the patient's genetic material, and is also not available as a treatment option in some countries. For this reason, new methods for early diagnosis, treatment, and prevention of POI are being developed. 
546 |a EN 
690 |a premature ovarian insufficiency 
690 |a premature ovarian insufficiency stem cells 
690 |a hormone replacement therapy 
690 |a infertility treatment 
690 |a early diagnosis 
690 |a egg donation 
690 |a Sports 
690 |a GV557-1198.995 
690 |a Sports medicine 
690 |a RC1200-1245 
655 7 |a article  |2 local 
786 0 |n Quality in Sport, Vol 9, Iss 2 (2023) 
787 0 |n https://apcz.umk.pl/QS/article/view/42706 
787 0 |n https://doaj.org/toc/2450-3118 
856 4 1 |u https://doaj.org/article/a38d0b80ed0240a984f6e6e7f28b24e5  |z Connect to this object online.