Advanced squamous cell carcinoma and immunotherapy: new therapeutic perspectives

Squamous cell carcinoma (SCC) has the second highest incidence rate among non-melanoma skin cancers. About 5% of cases progress to locally advanced and/or metastatic lesions, making the surgical approach often unfeasible. Based on this, we performed a literature review on the use of immunotherapy dr...

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Bibliographic Details
Main Authors: Magda Blessmann Weber (Author), Iago Gonçalves Ferreira (Author), Laura Oliveira Ferreira (Author), Anna Bittarello Silva (Author), Selma Schuartz Cernea (Author)
Format: Book
Published: Sociedade Brasileira de Dermatologia (SBD), 2021-12-01T00:00:00Z.
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Summary:Squamous cell carcinoma (SCC) has the second highest incidence rate among non-melanoma skin cancers. About 5% of cases progress to locally advanced and/or metastatic lesions, making the surgical approach often unfeasible. Based on this, we performed a literature review on the use of immunotherapy drugs to treat advanced SCC. The results showed that immunotherapy is a potential therapeutic strategy due to the antitumor activity promotion through the individual immune response, reducing the adverse events of surgeries, chemotherapy, and radiotherapy.
Item Description:1984-8773
10.5935/scd1984-8773.2021130023