Identification of a novel small-molecule inhibitor of miR-29b attenuates muscle atrophy

• Main Authors: Qi Liu (Author), Weilin Yuan (Author), Yuwei Yan (Author), Bing Jin (Author), Mengke You (Author), Tianqi Liu (Author), Mingchun Gao (Author), Jin Li (Author), Priyanka Gokulnath (Author), Gururaja Vulugundam (Author), Guoping Li (Author), Bin Xu (Author), Junjie Xiao (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Muscle atrophy is debilitating and can be induced by several stressors. Unfortunately, there are no effective pharmacological treatment until now. MicroRNA (miR)-29b is an important target that we identified to be commonly involved in multiple types of muscle atrophy. Although sequence-specific inhi...