The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney

• मुख्य लेखकों: Anna Zimnol (लेखक), Nora Spicker (लेखक), Ronja Balhorn (लेखक), Katrin Schröder (लेखक), Nicole Schupp (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In higher concentrations, the blood pressure regulating hormone angiotensin II leads to vasoconstriction, hypertension, and oxidative stress by activating NADPH oxidases which are a major enzymatic source of reactive oxygen species (ROS). With the help of knockout animals, the impact of the three pr...