The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington's disease brain
Abstract Background The mechanisms underlying neurodegeneration in the striatum of Huntingon's Disease (HD) brain are currently unknown. While the striatum is massively degenerated in symptomatic individuals, which makes cellular characterization difficult, it is largely intact in asymptomatic...
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Main Authors: | Filisia Agus (Author), Diego Crespo (Author), Richard H. Myers (Author), Adam Labadorf (Author) |
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Format: | Book |
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BMC,
2019-10-01T00:00:00Z.
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